# Observed Reduction in Urinary Toxin Excretion With Extracorporeal Blood Oxygenation and Ozonation (EBOO) Treatment in an 88-Year-Old With Chronic Anemia: A Case Report

## TL;DR

An 88-year-old with chronic anemia showed reduced urinary toxins after EBOO treatments, suggesting it may help detoxify patients with environmental exposures.

## Contribution

This case report demonstrates EBOO's potential to reduce toxin excretion in a patient with chronic anemia and environmental toxicity.

## Key findings

- Urinary mycotoxin levels decreased by 64.8% after two EBOO treatment series.
- Environmental toxin excretion dropped by 55.1% following EBOO therapy.
- Hemoglobin levels remained stable despite toxin reductions.

## Abstract

Extracorporeal blood oxygenation and ozonation (EBOO) is a hemodialysis-adjacent ex vivo filtration system. We present a case of an 88-year-old female with chronic iron-deficiency anemia with high urinary levels of mycotoxins, heavy metals, and other environmental toxins. She underwent two distinct series of three sequential EBOO treatments, with interval monitoring of her urinary toxin/creatinine ratios (µg/g) at baseline, after completion of EBOO series I, and after completion of EBOO series II. The average decline from baseline to completion of EBOO series II was 64.8% for the mycotoxins, 25.7% for the heavy metals, and 55.1% for the environmental toxins. Though there was no control for ongoing exposure, all of her toxin levels ultimately decreased except nickel. Her hemoglobin levels remained largely unchanged over the course of treatment. Thus, EBOO should be considered a potential therapy in patients with environmental toxicities that may be contributing to chronic conditions.