Retraction: Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells

Abstract

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Following the publication of this article [1] concerns were raised with results presented in Figs 1-3. Specifically:

The corresponding author stated that the panels included in [1] represent the original experimental outputs as obtained at the time of the study, with only uniform, global adjustments to brightness and contrast applied. They also stated that the underlying data for the above figures are no longer available. The corresponding author provided original plate images for Fig 2 which did not resolve the concerns.

In light of the above concerns which call into question the reliability and integrity of the published results, the PLOS One Editors retract this article.

DDA and RVI did not agree with the retraction. MF, AM, and RB did not agree with the retraction and stand by the article’s findings. JL, AV, MPG, PMC, BW, MR, DSB and LGG either did not respond directly or could not be reached.

The left and right Mitostatin and β-actin panels of Fig 1B report material similar to that published in Fig 6A in [2], published in 2008 by Springer Nature. The left and right Mitostatin and β-actin panels of Fig 1B are not offered under a CC BY license and are therefore excluded from this article’s [1] license.