# Combined leadless pacing and subcutaneous defibrillation strategy in a high-risk patient: first case report from Peru

**Authors:** Alexis Vallejos-Barrientos, Diego Davila-Flores, Richard Soto-Becerra, Mario Cabrera-Saldaña, Carolina Guevara-Caicedo, Ana Cecilia Gonzales-Luna, Ángel Cueva-Parra, Marisel Payano-Rojas, Pío Zelaya-Castro

PMC · DOI: 10.47487/apcyccv.v6i4.513 · Archivos Peruanos de Cardiología y Cirugía Cardiovascular · 2025-12-29

## TL;DR

A high-risk patient received a leadless pacemaker and subcutaneous defibrillator, avoiding infection and complications.

## Contribution

Demonstrates a novel sequential implantation strategy using leadless and subcutaneous devices in a high-risk patient.

## Key findings

- Sequential implantation of leadless pacemaker and subcutaneous defibrillator was successfully performed.
- Patient showed favorable recovery with no arrhythmic recurrences or infections at six months.
- Fully leadless approach is feasible for patients with contraindications to transvenous systems.

## Abstract

We present the case of a 51-year-old male with non-ischemic dilated cardiomyopathy and complete atrioventricular block, who was previously implanted with a cardiac resynchronization therapy defibrillator. The patient developed signs of pocket infection with a high risk of extrusion. Partial system extraction was performed, followed by 14 days of intravenous antibiotic therapy. Due to a history of ventricular fibrillation and permanent pacing dependency, and in the absence of viable transvenous access, a sequential implantation strategy was adopted using a leadless pacemaker (Micra AV, Medtronic) and a subcutaneous implantable cardioverter-defibrillator (EMBLEM, Boston Scientific). Both procedures were completed without complications, and the patient showed favorable recovery, with effective pacing, no arrhythmic recurrences, and no signs of infection at the six-month follow-up. This case illustrates the feasibility of a fully leadless approach in high-risk patients with contraindications to conventional transvenous systems.

## Linked entities

- **Diseases:** atrioventricular block (MONDO:0000465), ventricular fibrillation (MONDO:0000190)

## Full-text entities

- **Diseases:** atrioventricular block (MESH:D054537), pocket infection (MESH:D005888), dilated cardiomyopathy (MESH:D002311), arrhythmic (OMIM:212500), ventricular fibrillation (MESH:D014693), infection (MESH:D007239)
- **Chemicals:** implantable cardioverter (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12825431/full.md

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Source: https://tomesphere.com/paper/PMC12825431