# Relationship Between Anemia, and Serum Testosterone Levels in Chronic Obstructive Pulmonary Disease Patients: A Cross-sectional Study: -

## TL;DR

This study explores the link between anemia and testosterone levels in COPD patients, finding a significant association in females.

## Contribution

The study is one of the first to investigate the relationship between anemia and testosterone levels specifically in COPD patients.

## Key findings

- Females with anemia had significantly higher mean testosterone levels compared to those without anemia.
- No significant differences in testosterone levels were found between males with and without anemia.
- Anemia prevalence was similar in male and female COPD patients.

## Abstract

Chronic obstructive pulmonary disease (COPD) is a complex condition
that can be associated with various comorbidities, including anemia and
hormonal
imbalances. The relationship between COPD, anemia, and serum testosterone
levels
has not been thoroughly investigated. To examine the relationship between
COPD,
anemia, and serum testosterone levels in patients with COPD.

This cross-sectional study was conducted at Shahid Faghihi and Namazi
hospitals in Shiraz, Iran, and included 43 patients with COPD who were
admitted
to internal medicine and emergency departments between autumn 2018 and
autumn
2019. Patients were evaluated for anemia, and serum testosterone levels were
measured. Data were analyzed using SPSS version 22.

The study included 27 males (62.8%) and 16 females (37.2%). The prevalence of
anemia was 48.1%
(13/27) in males and 50% (8/16) in females. Total testosterone was
significantly
higher in males (M=1.74, SD=1.85) compared to females (M=0.47, SD=0.69),
P.001.
The study found that females with anemia had significantly higher mean
testosterone total levels compared to those without anemia (p=0.047).
However,
no significant differences were found in testosterone levels between males
with
and without anemia. While females with anemia had a mean total testosterone
level of 0.32 (SD=0.27), while those without anemia had a mean level of 0.61
(SD=0.91), with a significant P-value of 0.047.

This study suggests
a potential relationship between anemia and serum testosterone levels in
female
patients with COPD. Further research is needed to confirm these findings and
explore the underlying mechanisms.