# Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

**Authors:** Jiaqi Chen, Zejin Zhao, Kunyu Huang, Liyong Zhang, Jinhua Cui, Ziyu Bai, Aijun Yu, Jian Li, Zhuqing Zhang, Kai Chen

PMC · DOI: 10.3389/fmed.2025.1713210 · 2026-01-08

## TL;DR

A healthy young woman experienced a rare and life-threatening rupture of a liver abscess, leading to severe bleeding and infection requiring emergency surgery.

## Contribution

This is the first reported case of a ruptured pyogenic liver abscess complicated by massive subcapsular hematoma in a young immunocompetent woman.

## Key findings

- A healthy young woman developed hemorrhagic and septic shock from a ruptured liver abscess.
- Emergency laparoscopic surgery and ICU care successfully treated the condition with no long-term complications.
- The case highlights the need for early recognition and multidisciplinary management of such rare but severe events.

## Abstract

Bacterial and parasitic agents can cause liver abscess (LA), and spontaneous rupture of a pyogenic liver abscess (PLA) represents an exceedingly rare but life-threatening event. Upon abscess rupture, a sudden influx of pus and bacterial toxins into the peritoneal cavity can trigger a dysregulated host response to infection. Should major intrahepatic vessels be involved, life-threatening hemorrhagic shock may supervene, with clinical deterioration occurring within hours. We present the first case of a young woman with a ruptured liver abscess complicated by a massive subcapsular hematoma who rapidly developed hemorrhagic and septic shock and underwent emergency laparoscopic surgery followed by intensive care unit (ICU) admission. No adverse complications were observed in follow-ups at one, three, and six months after the operation. This case emphasizes that even immunocompetent young adults can experience acute abscess rupture with life-threatening hemorrhagic shock, mandating early recognition, prompt intervention, and multidisciplinary management.

## Full-text entities

- **Diseases:** LA (MESH:D008100), abscess rupture (MESH:D012421), hematoma (MESH:D006406), septic shock (MESH:D012772), infection (MESH:D007239), PLA (MESH:D046290), hemorrhagic shock (MESH:D012771), hemorrhagic (MESH:D006470)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12823863/full.md

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Source: https://tomesphere.com/paper/PMC12823863