# Endovascular treatment of diffuse mandibular arteriovenous malformation: a case report and literature review

**Authors:** Defu Dong, Kai Zheng, Bo Ma, Qiangqiang Nie, Xueqiang Fan, Peng Liu, Zhidong Ye

PMC · DOI: 10.3389/fcvm.2025.1640062 · 2026-01-08

## TL;DR

A rare case of a mandible arteriovenous malformation was successfully treated with endovascular techniques, preventing severe bleeding and showing no recurrence after one year.

## Contribution

Demonstrates the effectiveness of combined endovascular embolization and sclerotherapy for treating a rare mandibular AVM.

## Key findings

- Endovascular therapy with coil embolization and sclerotherapy achieved complete occlusion of the AVM.
- No recurrence was observed at 4 days, 6 months, and 1 year follow-up.
- The treatment avoided complications and provided durable control of the lesion.

## Abstract

Arteriovenous malformations (AVMs) are rare congenital vascular anomalies involving high-flow shunting between arteries and veins. Intraosseous AVMs of the mandible are particularly uncommon and present substantial diagnostic and therapeutic challenges. Because even minor trauma or dental procedures may trigger severe hemorrhage, early recognition and appropriate management are essential.

We describe a 33-year-old woman with a long-standing vascular lesion of the right mandible who developed uncontrolled oral bleeding after tooth extraction. Imaging confirmed a diffuse intraosseous AVM. After multiple unsuccessful treatments elsewhere, she underwent endovascular therapy consisting of super-selective arterial and venous access, coil embolization, and sclerotherapy with absolute ethanol and polidocanol foam. The procedure resulted in complete occlusion of the lesion without complications. Follow-up at 4 days, 6 months, and 1 year showed no recurrence.

Mandibular AVMs are complex lesions that carry a significant risk of life-threatening hemorrhage. This case demonstrates that combined endovascular embolization and sclerotherapy can provide effective and durable control. Accurate diagnosis, timely intervention, and continued follow-up are essential to achieving favorable outcomes for this rare condition.

## Linked entities

- **Chemicals:** absolute ethanol (PubChem CID 702)

## Full-text entities

- **Diseases:** Mandibular AVMs (MESH:D008338), vascular anomalies (MESH:D020785), bleeding (MESH:D006470), mandible (MESH:C563485), trauma (MESH:D014947), intraosseous AVM (MESH:D002538), vascular lesion (MESH:D014652), AVMs (MESH:D001165)
- **Chemicals:** polidocanol (MESH:D000077423), ethanol (MESH:D000431)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12823793/full.md

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Source: https://tomesphere.com/paper/PMC12823793