Retraction: Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug

Abstract

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Following the publication of this article [1], concerns were raised about results presented in Figs 4–7. Specifically:

The first author stated that the issues with Figs 4–7 are the result of figure preparation errors. They disagreed with the statistical concerns, stating that although some figures display multiple outcome measurements side-by-side, and some figures show multiple parameters in a single graph, only univariate comparisons were conducted separately for each parameter. The journal remains concerned about the statistical approach reported for this article. The first author stated that the data underlying the published results are no longer available. In the absence of the individual-level and image data for the figures of concern, the above concerns cannot be resolved.

In light of the above concerns, which raise questions about the reliability of the overall data handling and published results, the PLOS One Editors retract this article.

NP agreed with the retraction and apologizes for the issues with the published article. KRG, VKKM, ADN, NV, UB, and MPB either did not respond directly or could not be reached.