# A case series of Sneddon syndrome: clinical features, diagnostic workup, and literature review

## TL;DR

This paper presents six cases of Sneddon syndrome, highlighting its symptoms and the importance of early detection through skin exams in young stroke patients.

## Contribution

The study emphasizes the role of dermatological evaluation in diagnosing Sneddon syndrome in young stroke patients.

## Key findings

- Six women with Sneddon syndrome showed livedo racemosa and cerebrovascular disease.
- Dermatological exams helped identify the syndrome and influenced stroke treatment decisions.
- The paper reviews clinical features, diagnostics, and treatment options for Sneddon syndrome.

## Abstract

Sneddon syndrome, a rare, non-inflammatory thrombotic vasculopathy characterized by livedo racemosa and cerebrovascular disease.

We present a case series of six women diagnosed with Sneddon syndrome. We conducted a thorough analysis of clinical, radiological, and laboratory data, including results of prothrombotic and autoimmune screening. Our findings emphasize the importance of considering Sneddon syndrome as a potential cause of stroke, particularly in young women, and underscore the necessity of a comprehensive dermatological examination when evaluating stroke etiology. Additionally, we provide a comprehensive literature review of the clinical manifestations, radiological and histopathological findings, as well as treatment options.

A thorough dermatological examination can aid in early detection of Sneddon syndrome and may change the course of treatment of stroke in young adults.