# Overcoming Patient Access Barriers in Complex Conditions: Lessons from Schizophrenia for Broader Healthcare Applications

**Authors:** Saartje Burgmans, Anne Rieper Hald, Sayagi Tina Markandaier, Nicolas Hall, Rafael Loiseau, Xandra Lie, Bregt Kappelhoff

PMC · DOI: 10.3390/jmahp14010002 · Journal of Market Access & Health Policy · 2025-12-23

## TL;DR

This study explores barriers to schizophrenia care in Europe and suggests reforms to improve access to comprehensive treatment for complex conditions.

## Contribution

The paper identifies structural barriers to cognitive care in schizophrenia and proposes systemic reforms applicable to other complex conditions.

## Key findings

- Fragmented care pathways and insufficient cognitive assessment capacity hinder access to schizophrenia care.
- Reimbursement systems favor drugs over psychosocial interventions, limiting holistic treatment options.
- Stronger community infrastructure and broader reimbursement frameworks improve care delivery for complex conditions.

## Abstract

Patient access to innovative care for complex conditions like schizophrenia remains limited by systemic, clinical and policy-level barriers. Cognitive impairment associated with schizophrenia (CIAS) illustrates how critical symptom domains are often overlooked despite their impact on long-term outcomes. This study examines how systemic, infrastructural and economic factors shape access to CIAS care across eight mid-sized European countries to identify shared constraints and opportunities for improvement. Semi-structured interviews were conducted with 32 healthcare professionals and 9 health policy experts. Thematic analysis identified consistent barriers across countries, including fragmented care pathways, insufficient capacity for cognitive assessment, underdeveloped community-based rehabilitation services and reimbursement structures that favour pharmacological over psychosocial interventions. Variability across countries was shaped by differences in community infrastructure, professional training and the breadth of health technology assessment perspectives applied to non-pharmacological care. Countries with stronger community infrastructure and broader reimbursement frameworks were better positioned to deliver comprehensive care. These findings highlight that structural constraints, rather than clinical uncertainty, are the primary impediments to care in complex therapeutic areas. Addressing them will require coordinated reforms that strengthen early identification, expand multidisciplinary rehabilitation capacity and align reimbursement with functional and long-term outcomes.

## Linked entities

- **Diseases:** schizophrenia (MONDO:0005090)

## Full-text entities

- **Diseases:** Schizophrenia (MESH:D012559), CIAS (MESH:D003072)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12821714/full.md

## References

95 references — full list in the complete paper: https://tomesphere.com/paper/PMC12821714/full.md

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Source: https://tomesphere.com/paper/PMC12821714