# The Mouth–Mind Connection: Interplay of Oral and Mental Health in Older Adults

**Authors:** Alice Kit Ying Chan, Joanna Cheuk Yan Hui, Lindsey Lingxi Hu, Chun Hung Chu

PMC · DOI: 10.3390/geriatrics11010008 · Geriatrics · 2026-01-05

## TL;DR

This paper explores how oral and mental health are closely linked in older adults, and how improving both can enhance overall well-being and independence.

## Contribution

The paper emphasizes the bidirectional relationship between oral and mental health in older adults and proposes integrated care strategies to address systemic gaps.

## Key findings

- Untreated oral diseases worsen mental health conditions like depression and anxiety in older adults.
- Mental health issues reduce motivation for oral care, leading to deteriorated oral health.
- Integrated care models and policy reforms are needed to address the interconnected challenges of oral and mental health.

## Abstract

The global population aged 65 and older is expected to double from 761 million in 2021 to 1.6 billion by 2050. Despite often being treated separately in clinical practice and policy, oral health and mental health are fundamentally interconnected in older adulthood, forming a bidirectional relationship that exacerbates disability, social inequity, and systemic healthcare challenges. This narrative review aims to summarize the two-way relationship between mental and oral health and emphasize their combined impact on systemic health, social engagement, and independence among ageing populations. The bidirectional relationship has profound clinical significance. Untreated oral diseases induce chronic pain and cause social embarrassment, aggravating pre-existing depression and anxiety. Periodontal disease can worsen systemic conditions such as diabetes, cardiovascular disease, and dementia via a shared inflammatory pathway. Conversely, mental health issues—including depression, anxiety, cognitive decline, and the use of psychotropic medications—reduce motivation for oral care, prompt dental neglect, and affect salivary function, deteriorating oral health. Despite clear connections, systemic gaps persist, including fragmented healthcare systems, financial barriers, stigma, lack of awareness, and caregiver burnout. To address these challenges, strategies such as developing integrated care models to unify dental and mental health services, reforming policies to prioritize oral and mental health parity, advocating anti-stigma campaigns to clear the misconceptions, and implementing community-based healthcare programmes to reach underserved older adults are essential. By recognizing oral health as a vital component of mental resilience, societies can transform ageing into an era of empowered well-being, where the mouth–mind connection promotes holistic health rather than functional decline.

## Linked entities

- **Diseases:** depression (MONDO:0002050), anxiety (MONDO:0005618), diabetes (MONDO:0005015), cardiovascular disease (MONDO:0004995), dementia (MONDO:0001627)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), anxiety (MESH:D001007), oral diseases (MESH:D009059), burnout (MESH:D002055), Periodontal disease (MESH:D010510), cardiovascular disease (MESH:D002318), cognitive decline (MESH:D003072), depression (MESH:D003866), diabetes (MESH:D003920), dementia (MESH:D003704), chronic pain (MESH:D059350)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12821425/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12821425/full.md

## References

81 references — full list in the complete paper: https://tomesphere.com/paper/PMC12821425/full.md

---
Source: https://tomesphere.com/paper/PMC12821425