# Positional Vertigo in a Child with Hearing Loss

**Authors:** Melissa Blanco-Pareja, Alberto Vieco García, Teresa Perucho, Javier Santos, José Manuel Moreno-Villares, Nicolas Pérez-Fernández

PMC · DOI: 10.3390/audiolres16010004 · Audiology Research · 2025-12-23

## TL;DR

This paper describes a rare case of positional vertigo in a child with hearing loss caused by a genetic mutation.

## Contribution

The study reports a novel case linking a STRC gene deletion to positional vertigo and hearing loss in a child.

## Key findings

- A homozygous deletion in the STRC gene on chromosome 15 was found in a child with positional vertigo.
- The genetic mutation is associated with both hearing loss and vestibular dysfunction in the patient.

## Abstract

Background and Clinical Significance: Vestibular disorders in children are often overlooked, delaying treatment. Early diagnosis of benign paroxysmal positional vertigo (BPPV) allows for targeted maneuvers during acute episodes. Though rare, BPPV can occur in children due to stereocilin gene (STRC) deletions or variants, causing hearing loss and vestibular dysfunction. Case Presentation: This study highlights a case of recurrent vertigo linked to a homozygous deletion on chromosome 15 affecting the STRC gene.

## Linked entities

- **Genes:** STRC (stereocilin) [NCBI Gene 161497]
- **Diseases:** hearing loss (MONDO:0005365)

## Full-text entities

- **Genes:** STRC (stereocilin) [NCBI Gene 161497] {aka DFNB16}
- **Diseases:** Hearing Loss (MESH:D034381), Vertigo (MESH:D014717), BPPV (MESH:D065635), Vestibular disorders (MESH:D015837)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12821404/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12821404/full.md

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Source: https://tomesphere.com/paper/PMC12821404