# Imaging features of lacrimal gland disease

**Authors:** Carmelo Caltabiano, Khizar Rana, Alexander Buckby, Sandy Patel, Dinesh Selva

PMC · DOI: 10.3389/fopht.2025.1724513 · Frontiers in Ophthalmology · 2026-01-07

## TL;DR

This paper reviews imaging techniques and features to help diagnose different types of lacrimal gland diseases.

## Contribution

The paper systematically outlines key radiological features for distinguishing lacrimal gland masses.

## Key findings

- Ultrasound, CT, and MRI are essential for characterizing lacrimal gland masses.
- Radiological features like laterality and enhancement patterns help narrow differential diagnoses.
- Lobe involvement and lesion composition are critical for accurate diagnosis.

## Abstract

Lacrimal gland masses represent a diverse group of pathological processes, including inflammatory, lymphoproliferative, and neoplastic lesions. They often present as a palpable mass in the superolateral orbit. There is significant overlap in clinical presentation, and imaging with ultrasound, computed tomography, and magnetic resonance imaging is essential for further characterisation. Key radiological features such as laterality, lobe involvement, lesion composition, margin definition, enhancement pattern, and associated bony changes can significantly narrow the differential diagnosis. This review will describe the radiological features of lacrimal gland masses to guide decision-making.

## Full-text entities

- **Diseases:** lacrimal gland disease (MESH:C562407), Lacrimal gland masses (MESH:C536030), lymphoproliferative, and neoplastic lesions (MESH:D008232), inflammatory (MESH:D007249)

## Full text

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## Figures

15 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12819838/full.md

## References

186 references — full list in the complete paper: https://tomesphere.com/paper/PMC12819838/full.md

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Source: https://tomesphere.com/paper/PMC12819838