# Case Report: Persistent delusional memories after postoperative delirium in a woman with complex cardiac surgical history

**Authors:** Aleksandra Stańska, Andrzej Klapkowski, Wojciech Karolak, Maciej Brzeziński

PMC · DOI: 10.3389/fpsyt.2025.1743329 · Frontiers in Psychiatry · 2026-01-07

## TL;DR

A woman with a complex cardiac history developed persistent delusional memories after delirium following surgery, which were later reframed as mental health symptoms.

## Contribution

The paper presents a rare case of long-lasting delusional memories after delirium and emphasizes the need for interdisciplinary care and follow-up.

## Key findings

- Delirium-related delusions can consolidate into persistent autobiographical memories.
- Interdisciplinary collaboration is crucial for managing delirium aftermath.
- Psychoeducation and follow-up can aid in reframing delusional memories.

## Abstract

Delirium is common after cardiac surgery and is associated with long-term cognitive and psychological morbidity. Many patients later recall vivid, often frightening delusional experiences, but sustained delusional conviction in such memories long after delirium resolution is rarely reported.

We describe a woman in her late 60s with congenital aortic valve disease, three previous aortic valve operations and a recent tricuspid valve repair via right mini-thoracotomy. Her postoperative course was severely complicated by hemothorax, repeated thoracotomies, respiratory failure, sepsis, acute kidney injury, anemia and malnutrition, together with exposure to multiple centrally acting drugs (benzodiazepines, opioids, pregabalin, dexmedetomidine). While being treated on a general cardiothoracic ward she developed delirium, with disorientation, sleep-wake disruption and prominent persecutory and somatic delusions that staff were mocking her, taking humiliating photographs and “videos”, and forcing tablets into her throat. Delirium resolved with optimization of medical status, reduction of deliriogenic medications and short-term low-dose olanzapine, yet she retained a fixed belief that these ward events had truly occurred. For almost a year, including during a later admission for prosthetic valve endocarditis with paravalvular leak and an unsuccessful percutaneous closure attempt, she repeatedly reported these experiences as factual abuse despite psychotherapy and psychoeducation. Only during a subsequent elective admission, when reconsidering a high-risk redo valve operation that she ultimately declined, did she spontaneously reframe the memories as symptoms of “a mental disorder” and apologize to staff.

This case highlights how delirium-related persecutory experiences can consolidate into persistent trauma-like autobiographical memories with prolonged delusional conviction, and underscores the need for structured delirium follow-up, explicit psychoeducation for patients and families, and close collaboration between cardiology, cardiac surgery, psychiatry and psychology.

## Linked entities

- **Chemicals:** opioids (PubChem CID 126961754), pregabalin (PubChem CID 4715169), dexmedetomidine (PubChem CID 5311068), olanzapine (PubChem CID 135398745)
- **Diseases:** respiratory failure (MONDO:0021113), acute kidney injury (MONDO:0002492), anemia (MONDO:0002280), malnutrition (MONDO:0006873)

## Full-text entities

- **Diseases:** delusional (MESH:D012563), acute kidney injury (MESH:D058186), paravalvular leak (MESH:D019559), respiratory failure (MESH:D012131), aortic valve disease (MESH:D000082862), sepsis (MESH:D018805), abuse (MESH:D019966), hemothorax (MESH:D006491), trauma (MESH:D014947), Delirium (MESH:D003693), malnutrition (MESH:D044342), anemia (MESH:D000740), prosthetic valve endocarditis (MESH:D004696), sleep-wake disruption (MESH:D012893), postoperative delirium (MESH:D000071257), mental disorder (MESH:D001523), delusions (MESH:D063726)
- **Chemicals:** benzodiazepines (MESH:D001569), dexmedetomidine (MESH:D020927), pregabalin (MESH:D000069583), olanzapine (MESH:D000077152)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12819823/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12819823/full.md

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Source: https://tomesphere.com/paper/PMC12819823