# Prevalence of vitamin D deficiency and related factors among adults in Tokat province, Türkiye: a community-based cross-sectional study

**Authors:** Muzaffer Katar, Rıza Çıtıl, Yalçın Önder, Osman Demir

PMC · DOI: 10.3389/abp.2025.15459 · Acta Biochimica Polonica · 2026-01-07

## TL;DR

This study found high rates of vitamin D deficiency in adults in Tokat, Türkiye, with women, older adults, and obese individuals being most affected.

## Contribution

The study provides new data on vitamin D deficiency prevalence and risk factors in an under-researched adult population in Türkiye.

## Key findings

- 38.7% of participants had vitamin D deficiency and 46.4% had insufficiency.
- Female sex, obesity, and lower education were independent predictors of deficiency.
- Public health interventions should target high-risk groups like women and older adults.

## Abstract

Vitamin D deficiency is a major public health concern, worldwide yet data on the adult population in Türkiye remain limited. This study aimed to determine the prevalence of vitamin D deficiency and its associated risk factors in Tokat Province, Türkiye.

A population based cross-sectional study was conducted among 2,225 adults aged ≥20 years through multistage stratified cluster sampling from both urban and rural areas. Data were obtained via structured questionnaires, anthropometric measurements, and fasting blood samples. Serum 25-hydroxyvitamin D3 [25(OH)D3] levels were measured and categorized as deficient (<10 ng/mL), insufficient (10–20 ng/mL), or sufficient (>20 ng/mL). Multivariate logistic regression was used to identify predictors of deficiency.

The mean age was 47.2 ± 15.2 years, and 54.8% were women. Vitamin D deficiency was present in 38.7% and insufficiency in 46.4% of participants. Deficiency was significantly more common among women, the older adult, obese individuals, and those with lower education levels and chronic diseases (p < 0.05). In the adjusted model female sex (aOR 0.19, 95% CI 0.14–0.27), obesity (aOR 1.76, 95% CI 1.36–2.28), and lower education were independent predictors of deficiency.

Vitamin D deficiency and insufficiency are highly prevalent among adults in Tokat Province, despite adequate sunlight exposure in the region. Public health strategies/interventions should focus on high-risk groups, prioritize particularly women, older adults, and obese individuals through screening, education, and targeted supplementation.

## Full-text entities

- **Diseases:** Vitamin D deficiency (MESH:D014808), obese (MESH:D009765)
- **Chemicals:** 25(OH)D3 (MESH:D002112)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12819332/full.md

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Source: https://tomesphere.com/paper/PMC12819332