# Recent efficacy of modified right vertical infra-axillary thoracotomy for ventricular septal defects in pediatric patients with younger age and Low body weight

**Authors:** Heqi Zhang, Hua Cao, Weijie Liang, Taibing Fan

PMC · DOI: 10.3389/fped.2025.1683641 · Frontiers in Pediatrics · 2026-01-07

## TL;DR

A modified surgical approach for repairing heart defects in infants under six months old is shown to be safe and effective, with faster recovery and fewer complications.

## Contribution

The study demonstrates the modified right vertical infra-axillary thoracotomy as a viable alternative to traditional sternotomy for infants with low body weight.

## Key findings

- MRVIAT reduced operation time, bleeding, and hospital costs compared to median sternotomy.
- MRVIAT patients had shorter ICU stays and faster extubation rates.
- No significant differences in pulmonary function or complication rates were observed between the groups.

## Abstract

To evaluate the safety and efficacy of a modified right vertical infra-axillary thoracotomy (MRVIAT) technique for treating ventricular septal defects (VSD) in infants younger than six months. and low body weight (≤5 kg).

From January 2020 to December 2024, the study included 204 infants who underwent MRVIAT and 62 infants who underwent median sternotomy (MS). General, perioperative, and follow-up data were analyzed retrospectively.

Operation time, intraoperative bleeding, 24-h postoperative chest tube drainage, mechanical ventilation time, postoperative intensive care unit time, extubation rate within 24 h postoperatively, hospital costs, and incision length were shorter in the MRVIAT group than in the MS group (P < 0.05). Peak airway pressure, lung dynamic compliance (Cdyn), and oxygenation index were similar in both groups at preoperative and postoperative time points (P > 0.05). There were no deaths in either group, and there was no significant difference in complication rates (P > 0.05). At 60 months (with a median follow-up of 25 months), two cases of sternal deformity occurred in the MS group, but none occurred in the MRVIAT group.

ventricular septal defect repair by MRVIAT in younger children with low body weight is less invasive. It provides good incision exposure, does not affect pulmonary function, reduces intraoperative bleeding and postoperative hospital stay and costs, and facilitates rapid recovery. This procedure is safe and effective and can be considered an alternative to median sternotomy.

## Linked entities

- **Diseases:** ventricular septal defects (MONDO:0002070)

## Full-text entities

- **Diseases:** VSD (MESH:D006345), bleeding (MESH:D006470), deaths (MESH:D003643), sternal deformity (MESH:C537489)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12819211/full.md

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Source: https://tomesphere.com/paper/PMC12819211