# A case of isolated testicular Tuberculosis: Approach and management

**Authors:** Ismail Mahad Abdullahi, Ismail Ahmed Ali, Abdirahin Mohamed Abdulkadir, Rahma Abdukadir Ahmed, Abdullahi Hassan Elmi

PMC · DOI: 10.1016/j.eucr.2025.103328 · Urology Case Reports · 2025-12-23

## TL;DR

This paper presents a rare case of testicular tuberculosis and discusses its diagnosis and treatment.

## Contribution

The novelty lies in highlighting testicular TB as a possible cause of chronic scrotal swelling in TB-endemic regions.

## Key findings

- Testicular TB can present as chronic scrotal swelling without systemic symptoms.
- Histopathology confirmed granulomatous inflammation with caseous necrosis consistent with TB.
- Orchiectomy followed by anti-tubercular therapy was effective in this case.

## Abstract

Testicular tuberculosis is a rare form of genitourinary TB that often mimics conditions such as neoplasms or chronic epididymo-orchitis, making diagnosis challenging. We report a 60-year-old man with longstanding right testicular pain and swelling, no systemic symptoms, and a history of household TB exposure. Imaging showed a large hydrocele with suspected underlying pathology. Intraoperative findings revealed necrotic testicular tissue, prompting orchiectomy. Histopathology confirmed granulomatous inflammation with caseous necrosis consistent with TB. The patient began standard anti-tubercular therapy. This case highlights the need to consider testicular TB in chronic scrotal swelling, particularly in TB-endemic settings.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** epididymo-orchitis (MESH:D009920), necrotic testicular tissue (MESH:D013733), scrotal swelling (MESH:D014063), neoplasms (MESH:D009369), TB (MESH:D014390), Testicular tuberculosis (MESH:D014376), genitourinary TB (MESH:D000091642), hydrocele (MESH:D006848), swelling (MESH:D004487), granulomatous (MESH:D013968), necrosis (MESH:D009336), testicular pain (MESH:D010146), inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12819019/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12819019/full.md

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Source: https://tomesphere.com/paper/PMC12819019