# MSC-EVs alleviate osteoarthritic joint pain and degeneration by suppressing IL-1β/NGF signaling

**Authors:** Kristeen Ye Wen Teo, Chengming Wen, Raymond Chung Wen Wong, Wei Seong Toh

PMC · DOI: 10.1016/j.gendis.2025.101981 · Genes & Diseases · 2025-12-11

## Full-text entities

- **Genes:** IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, NGF (nerve growth factor) [NCBI Gene 4803] {aka Beta-NGF, HSAN5, NGFB}
- **Diseases:** osteoarthritic joint pain (MESH:D018771)

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## References

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Source: https://tomesphere.com/paper/PMC12818981