# Patient preferences for incentives in Contingency Management interventions in methadone treatment: A best-worst scale analysis

**Authors:** Thuy Thi Dieu Dao, Hue Thi Nguyen, Trang Thu Nguyen, Thuyet Thi Phung, Van Hai Hoang, Huong Thi Le, Brian W. Pence, Giang Minh Le, Vivian F. Go, William C. Miller, Kimberly Page, Kimberly Page, Kimberly Page, Kimberly Page

PMC · DOI: 10.1371/journal.pone.0341359 · PLOS One · 2026-01-20

## TL;DR

This study identifies patient preferences for low-cost incentives in methadone treatment to improve adherence and retention.

## Contribution

The study quantifies patient preferences for low-cost incentives in methadone treatment using best-worst scale analysis.

## Key findings

- Discounts for monthly methadone fees were the most preferred incentive.
- Take-home methadone privileges and priority coupons for early checkups were also highly preferred.
- Community or clinic recognition was among the least preferred incentives.

## Abstract

Contingency management (CM) effectively enhances adherence and retention in methadone maintenance treatment (MMT). But implementing CM in resource-limited settings is challenging, particularly due to costs associated with providing incentives. In this study, we aimed to describe and quantify patient preferences regarding low-cost CM incentives to promote adherence and retention in MMT.

We conducted a cross-sectional survey using a best-worst scale (case 1) among 216 participants ages 18 or older undergoing MMT in six clinics in Hanoi, Vietnam. The study asked participants to complete 13 sets of best-worst scaling tasks. Each task presented a subset of four incentives chosen from a total of 13 incentives. Net scores for each incentive were calculated by subtracting the total times an incentive was rated as least appealing from the total times it was rated as most appealing. Standardized scores were derived by dividing the net score by the sum of selections and then converted to weighted probabilities (WP) that ranged from 0% to 100% (example interpretation: an incentive with WP of 20% is twice as desired as an incentive with WP of 10%). The 95% confidence intervals (95% CI) were estimated using bootstrapping.

The mean age of participants was 44.7 (SD = 8.0, range: 25–66). Most were male (95%), married (59%), and had not completed high school (69%). About half (50%) had been on methadone treatment for more than five years. The most preferred incentives were “discount for monthly methadone fees” (WP = 16.9, 95% CI: 16.0, 17.8) and “take-home methadone privileges” (WP = 11.3, 95% CI: 10.1, 12.6), followed by “priority coupons for early medical examinations/consultations”. In contrast, the least preferred incentives were “being recognized/praised in their community” (WP = 4.5, 95% CI: 4.0, 5.0) and “being recognized/praised at their clinic” (WP = 4.7, 95% CI: 4.1, 5.4).

Treatment fee support, take-home methadone privilege, and coupons for prioritizing checkup at clinics emerged as the most desirable incentives for patients. We recommend future CM intervention may consider using these incentives as the first-line rewards to offer to reinforce treatment adherence and retention in methadone treatment. These findings suggest potential low-cost CM strategies that could inform decision-making in MMT programs.

## Full-text entities

- **Chemicals:** methadone (MESH:D008691)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12818641/full.md

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Source: https://tomesphere.com/paper/PMC12818641