This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: Genome-wide identification of RETINOBLASTOMA RELATED 1 binding sites in Arabidopsis reveals novel DNA damage regulators
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsRetinoids in leukemia and cellular processes · Cell death mechanisms and regulation · DNA Repair Mechanisms
After this article [1] was published, the corresponding author contacted the journal to raise concerns about the integrity and reliability of the results in [1], specifically regarding image overlap in panels describing different experimental conditions in Fig 9C of [1] and Fig EV1B of [2] (withdrawn in [3]), and to request that the journal conduct a further assessment of the images in the article. PLOS noted that in Figs 7 and 9, the following panels appear to partially or fully overlap:
The corresponding author agreed with the above image concerns and noted that the data underlying Figs 7, 8, 9C, and S10-S12 are no longer available. They also stated that they consider that the ChIP data and the article’s main conclusion remains valid, including the claim that these data could be used to identify new DNA damage regulators, and that original data are available to support the article’s other results (Figs 1-6, 9A-B, Figs S1-S9 and S13, Tables S1-S5, Appendices S1 and S2).
In light of the above unresolved concerns about Figs 7 and 9, the PLOS Genetics Editors retract this article.
DB, MH, HH, FR, CG, and AS agreed with the retraction. PC either did not respond directly or could not be reached.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Bouyer D, Heese M, Chen P, Harashima H, Roudier F, Grüttner C, et al. RETRACTED: Genome-wide identification of RETINOBLASTOMA RELATED 1 binding sites in Arabidopsis reveals novel DNA damage regulators. P Lo S Genet. 2018;14(11):e 1007797. doi: 10.1371/journal.pgen.1007797 30500810 PMC 6268010 · doi ↗ · pubmed ↗
- 2Chen P, De Winne N, De Jaeger G, Ito M, Heese M, Schnittger A. KNO 1-mediated autophagic degradation of the Bloom syndrome complex component RMI 1 promotes homologous recombination. EMBO J. 2023;42(10):e 111980. doi: 10.15252/embj.2022111980 36970874 PMC 10183828 · doi ↗ · pubmed ↗
- 3Chen P, De Winne N, De Jaeger G, Ito M, Heese M, Schnittger A. Withdrawal Note: KNO 1-mediated autophagic degradation of the Bloom syndrome complex component RMI 1 promotes homologous recombination. EMBO J. 2025;45(1):353. doi: 10.1038/s 44318-025-00500-6 41310088 PMC 12759064 · doi ↗ · pubmed ↗