# Spontaneous splenic rupture: a sporadic presentation of tuberculosis—a case report

**Authors:** Zeru A Sambi, Mehari A Tsegay

PMC · DOI: 10.1093/jscr/rjaf1103 · Journal of Surgical Case Reports · 2026-01-20

## TL;DR

A rare case of spontaneous splenic rupture caused by tuberculosis in an HIV-positive woman is reported, highlighting the importance of early diagnosis in immunocompromised patients.

## Contribution

This is the third reported case of spontaneous splenic rupture due to tuberculosis, emphasizing its rarity and diagnostic challenges.

## Key findings

- A 50-year-old HIV-positive woman presented with symptoms leading to the diagnosis of a ruptured tuberculous spleen.
- Histopathology confirmed splenic tuberculosis after emergency splenectomy.
- Spontaneous splenic rupture is exceptionally rare and often difficult to diagnose in immunocompromised individuals.

## Abstract

Atraumatic or spontaneous splenic rupture is a rare but life-threatening emergency. Common causes include hematologic malignancies and infections, but tuberculous involvement of the spleen is exceedingly uncommon. To our knowledge, this represents the third reported case of spontaneous rupture of a tuberculous spleen. We report a 50-year-old human immunodeficiency virus (HIV) -positive woman who presented with cough, fever, and abdominal distension, with abdominal examination suggesting peritoneal irritation and laboratory tests showing severe anemia. Emergency laparotomy revealed a ruptured spleen with 500 ml of hemolyzed blood, and splenectomy was performed. Histopathology confirmed splenic tuberculosis. The postoperative course was uneventful. Splenic tuberculosis typically occurs in disseminated disease among immunocompromised individuals. Fever of unknown origin is the commonest presentation; spontaneous rupture is exceptionally rare and difficult to diagnose. Although antitubercular therapy is the mainstay of treatment, hemodynamically unstable patients require surgery. Spontaneous splenic rupture should be considered in immunocompromised patients with an acute abdomen, as early recognition is lifesaving.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** infections (MESH:D007239), splenic rupture (MESH:D013161), abdominal distension (MESH:D000007), anemia (MESH:D000740), tuberculous (MESH:D014390), peritoneal irritation (MESH:D010538), tuberculosis (MESH:D014376), hematologic malignancies (MESH:D019337), cough (MESH:D003371), tuberculous spleen (MESH:D013160), Splenic tuberculosis (MESH:D014400), rupture (MESH:D012421), acute abdomen (MESH:D000006), Fever (MESH:D005334)
- **Species:** Human immunodeficiency virus (species) [taxon 12721], Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12818014/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12818014/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12818014/full.md

---
Source: https://tomesphere.com/paper/PMC12818014