# Comparison of Detection Yields Between Texture and Color Enhancement Imaging Mode 1 and Mode 2 for Colorectal Lesions: A Post‐hoc Analysis of a Multicenter Observational Study

## TL;DR

This study compares two imaging modes in colonoscopy for detecting colorectal lesions and finds no significant difference in detection rates.

## Contribution

The study provides a direct comparison of detection yields between two texture and color-enhancement imaging modes in colonoscopy.

## Key findings

- No statistically significant difference in mean number of adenomas detected per procedure between TXI1 and TXI2.
- Adenoma detection rates were comparable between TXI1 and TXI2 groups.
- Flat adenoma detection rates were slightly higher in TXI1 but not significantly different.

## Abstract

Colonoscopy is a reliable technique for the detection, diagnosis, and treatment of adenomas and early cancer. Image‐enhanced endoscopy (IEE) is important for detecting colorectal lesions. Texture and color‐enhancement imaging (TXI) has recently emerged as a novel modality for IEE. Thus, TXI operates in two modes: mode 1 (TXI1) enhances the structure, color, and brightness, whereas mode 2 (TXI2) does not. We have previously reported the detection of colorectal adenomas using TXI. We aimed to determine the detection yields of TXI1 and TXI2 using the data from our previous study.

We retrospectively analyzed the colonoscopy data from three institutions between August 2020 and January 2021. The patients were classified into two groups: TXI1 and TXI2. The mean number of adenomas detected per procedure (MAP), adenoma detection rate (ADR), and flat adenoma detection rate (FDR) were compared between groups.

The evaluations (95% confidence intervals) for the TXI1 versus TXI2 groups were as follows: MAP, 1.5 (1.3–1.7) versus 1.5 (1.3–1.7); ADR, 56.8% (47.3–65.9) versus 59.7% (50.3–68.6); and FDR, 68.6% (59.5–76.9) versus 63.9% (54.6–72.5), with no statistically significant differences between the groups.

The detection rates of colorectal lesions were comparable between the TXI1 and TXI2 groups.