# Interstitial pneumonitis following the implantation of a paclitaxel-eluting stent in a patient with peripheral arterial disease

## TL;DR

A patient developed lung inflammation after a stent implant, possibly due to an excessive dose of paclitaxel.

## Contribution

Highlights a rare but serious hypersensitivity reaction to paclitaxel in peripheral arterial disease treatment.

## Key findings

- Interstitial pneumonitis occurred after paclitaxel-eluting stent implantation with an overdose.
- Elevated Krebs von den Lungen-6 levels confirmed hypersensitivity.
- Symptoms improved with corticosteroid therapy.

## Abstract

We report a case of interstitial pneumonitis after paclitaxel-eluting stent implantation for peripheral arterial disease in a 74-year-old man. Five weeks after the procedure, the patient developed dyspnea and bilateral ground-glass opacities, with a paclitaxel dose (1169 μg) exceeding the recommended limit (1034 μg). Hypersensitivity to paclitaxel likely caused interstitial pneumonitis, confirmed by elevated Krebs von den Lungen-6 levels and exclusion of other etiologies. Corticosteroid therapy improved symptoms. Clinicians should monitor for rare but serious paclitaxel-induced pulmonary hypersensitivity in patients with peripheral arterial disease.