# Clinical outcomes of the single-stage revision technique in conversion total hip arthroplasty after failed femoral neck fractures: a two-year follow-up study

**Authors:** Jiankang Pan, Yongqiang Sun, Shuailei Li

PMC · DOI: 10.1186/s42836-025-00364-5 · 2026-01-19

## TL;DR

A study found that a single-stage revision technique during hip replacement surgery after failed femoral neck fractures may lower infection rates compared to traditional methods.

## Contribution

The study introduces the single-stage revision technique as a novel approach to reduce periprosthetic joint infections in conversion total hip arthroplasty.

## Key findings

- Group B (single-stage revision) had a 1% infection rate compared to 7% in Group A.
- 91% of Group B patients had no unexpected positive intraoperative cultures.
- The technique shows potential for reducing periprosthetic joint infections in this clinical scenario.

## Abstract

Conversion to total hip arthroplasty (THA) is associated with higher rates of infection. The purpose of this study is to determine whether applying the surgical technique of single-stage revision can effectively reduce the infection rate of conversion THA after failed femoral neck fractures.

A retrospective cohort study was conducted on patients who underwent conversion THA after failed femoral neck fracture between January 2019 and December 2022, with a minimum follow-up of 2 years. From January 2019 to March 2020, patients undergoing conversion THA were managed as a primary procedure without synovial fluid culture (Group A). From April 2020 to December 2022, patients undergoing conversion THA were managed with the single-stage revision technique and routine intraoperative synovial fluid culture (Group B). The patients in Group B were matched 1:1 to patients in Group A. Unexpected positive intraoperative culture (UPIC) results were recorded, and PJIs were monitored during the minimum 2-year follow-up period.

As intraoperative cultures were only performed in Group B, the unexpected positive intraoperative culture (UPIC) results presented were solely for Group B. Among the patients in Group B who underwent conversion THA, 91% had no UPIC (90 of 99), 7% had a single (either anaerobic bottle or aerobic bottle) UPIC (7 of 99), and 2% had two (both anaerobic and aerobic bottles) UPICs (2 of 99). In Group A, 7 patients (7/99, 7%) experienced PJIs, compared to 1 patient (1/99, 1%) in Group B, showing a significant difference between the two groups (P = 0.030).

As a novel method for conversion to THA after failed femoral neck fracture, the single-stage revision technique is potentially associated with a lower incidence of PJI. Further evaluation of this technique in larger comparative series is warranted.

Video Abstract

Video Abstract

The online version contains supplementary material available at 10.1186/s42836-025-00364-5.

## Full-text entities

- **Genes:** CCS (copper chaperone for superoxide dismutase) [NCBI Gene 9973], CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** avascular necrosis (MESH:D010020), pain (MESH:D010146), dislocation (MESH:D004204), femoral neck fracture (MESH:D005265), acute inflammation (MESH:D007249), fracture (MESH:D050723), varus (MESH:D060905), acetabular fracture (OMIM:142700), THA (MESH:D025981), COPD (MESH:D029424), UPIC (MESH:D000080485), nonunion (MESH:C538144), leg discrepancy (MESH:D010264), sepsis (MESH:D018805), rheumatoid arthritis (MESH:D001172), staphylococcus epidermidis (MESH:D013203), systemic lupus erythematosus (MESH:D008180), PJI (MESH:C537702), infected (MESH:D007239), PJI (MESH:D057068), SSI (MESH:D013530), dry (MESH:D015352), bacterial (MESH:D001424), Musculoskeletal Infection (MESH:D009140)
- **Chemicals:** calcium sulfate (MESH:D002133), hydrogen peroxide (MESH:D006861), saline (MESH:D012965), methicillin (MESH:D008712), cefazolin (MESH:D002437), vancomycin (MESH:D014640), betadine (MESH:D011206)
- **Species:** Cutibacterium acnes (species) [taxon 1747], Homo sapiens (human, species) [taxon 9606], Staphylococcus aureus (species) [taxon 1280], Staphylococcus epidermidis (species) [taxon 1282], aureus [taxon 46170]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12814572/full.md

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Source: https://tomesphere.com/paper/PMC12814572