# Limb salvage in multiple revision total knee arthroplasty using customised implants: When sleeves and cones are no longer an option

**Authors:** Stefanie Donner, Clemens Gwinner, Henryk Haffer, Carsten Perka, Stephanie Kirschbaum

PMC · DOI: 10.1002/jeo2.70647 · 2026-01-19

## TL;DR

Custom implants help in complex knee surgeries when standard options fail, showing improved patient outcomes in a small study.

## Contribution

Customized implants offer a new solution for severe bone defects in multiple knee revisions where standard implants fail.

## Key findings

- Custom implants improved KOOS scores from 31 to 80 and reduced pain significantly.
- Three out of 18 surgeries (17%) experienced complications like infection or fractures.
- Custom implants provided better fit in severe bone defects classified as AORI type III.

## Abstract

Multiple revision total knee arthroplasty (rTKA) remains highly challenging due to severe bone defects, which often render standard implants unsuitable. This study aimed to evaluate the clinical outcomes, survivorship and complication rates of customised knee implants used in aseptic one‐stage rTKA for patients with severe bone defects.

This study included 16 patients who underwent 18 one‐stage rTKAs using custom‐made implants due to aseptic loosening between 2016 and 2023. Conventional revision systems failed to provide appropriate femoral or tibial fixation due to severe conical longitudinal bone defects classified as Anderson Orthopaedic Research Institute (AORI) type III. Clinical outcomes were assessed using the knee injury and osteoarthritis outcome score (KOOS), Oxford knee score (OKS), visual analogue scale (VAS) for pain, range of motion (ROM), walking time and procedure‐related complications. Implant costs were compared between customised and standard implants.

Mean follow‐up was 51 months (range, 24–100), with patients having an average of five previous surgeries (range, 2–8). During follow‐up, three patients (17%) reported complications: one periprosthetic fracture, one periprosthetic joint infection and one failure of the modular stem component. Mean KOOS improved from 31 to 80 (p < 0.001), OKS from 47–32 points (p < 0.001) and pain on the VAS decreased from 8.1 to 3.1 (p < 0.001).

Customised implants for one‐stage rTKA present a promising cementless fit‐and‐fill fixation option for patients with severe longitudinal bone defects, particularly when standard knee revision implants, including cones and sleeves, are no longer suitable. Yet, these results are just midterm and small sample size‐based and therefore long‐term results in larger patient numbers need to be awaited before a final conclusion can be made.

Level IV.

## Full-text entities

- **Diseases:** periprosthetic fracture (MESH:D057068), osteoarthritis (MESH:D010003), aseptic loosening (MESH:D011475), bone defects (MESH:D001847), Anderson Orthopaedic (MESH:C535460), complication (MESH:D008107), pain (MESH:D010146), knee injury (MESH:D007718)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12814209/full.md

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Source: https://tomesphere.com/paper/PMC12814209