# Mild Subarachnoid Hemorrhage (SAH) With Low Hounsfield Unit Value (HUV) or Hijdra Scores Still Carries Outcome Risk: A Subgroup Analysis

**Authors:** Yushin Takemoto

PMC · DOI: 10.7759/cureus.99623 · 2025-12-19

## TL;DR

Mild subarachnoid hemorrhage with low clot volume or density still carries significant risk of poor outcomes, especially in elderly patients.

## Contribution

This study identifies that mild SAH with low Hijdra scores or HUV does not reliably predict a benign course, challenging current risk assessments.

## Key findings

- 28.3% of patients with Hijdra 0-19 and 29.4% with IT-HUV <46 had poor outcomes.
- Age was the strongest predictor of outcome, while IT-HUV lost discriminatory power in these subgroups.
- Intraventricular hemorrhage added modest but clinically relevant risk information.

## Abstract

The prognostic value of the initial Hounsfield unit value (IT-HUV) in aneurysmal subarachnoid hemorrhage (SAH) has been demonstrated in previous work, but it remains uncertain whether patients with mild clinical presentation and low clot burden can truly be considered low risk. To address this question, we analyzed two subgroups of WFNS 1-2 patients: (1) limited hemorrhage volume (Hijdra 0-19; n = 46) and (2) low hemorrhage density (IT-HUV <46; n = 51). Despite their favorable initial appearance, both subgroups exhibited substantial rates of poor outcome, occurring in 13/46 (28.3%) and 15/51 (29.4%), respectively, while delayed cerebral ischemia (DCI) and symptomatic vasospasm (SVS) also occurred with nonnegligible frequency. Within these restricted cohorts, IT-HUV no longer demonstrated meaningful discriminatory ability, whereas age consistently remained the strongest predictor of outcome. Intraventricular hemorrhage contributed modest but clinically relevant additional risk information. These findings indicate that mild SAH accompanied by low-volume or low-density hemorrhage does not reliably correspond to a benign course. Elderly patients, particularly those with intraventricular extension, may still be vulnerable to complications and therefore warrant careful clinical monitoring rather than exclusion from vasospasm prophylaxis based solely on initial mild features.

## Linked entities

- **Diseases:** subarachnoid hemorrhage (MONDO:0005099)

## Full-text entities

- **Diseases:** SVS (MESH:D020301), SAH (MESH:D013345), hemorrhage (MESH:D006470), DCI (MESH:D002545), Intraventricular hemorrhage (MESH:D000074042)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12813990/full.md

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Source: https://tomesphere.com/paper/PMC12813990