# Introduction of methicillin-resistant Staphylococcus aureus (MRSA) nasal polymerase chain reaction testing combined with pharmacist ordering and intervention reduces anti-MRSA antibiotic use in a multi-hospital system

## TL;DR

A new approach using MRSA nasal testing and pharmacist oversight reduced MRSA antibiotic use across multiple hospitals.

## Contribution

Combining MRSA nasal PCR testing with pharmacist intervention significantly reduced anti-MRSA antibiotic use in a multi-hospital system.

## Key findings

- Implementation led to a 20.2% reduction in anti-MRSA antibiotic use.
- 17 of 23 patient care units saw significant reductions.
- The approach is effective for antimicrobial stewardship in multi-center settings.

## Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) nasal polymerase chain reaction implementation combined with pharmacist oversight across four hospitals resulted in a 20.2% reduction in anti-MRSA agent standardized antimicrobial administration ratios with significant reductions across 17 of 23 patient care units, further supporting this approach as an effective, multi-center, antimicrobial stewardship strategy.