# The seminal plasma proteome dataset of the giant panda

## TL;DR

This study identifies 1125 proteins in giant panda seminal plasma, offering insights into their reproductive biology and aiding conservation efforts.

## Contribution

The first proteomic analysis of giant panda seminal plasma, revealing unique proteins and their potential roles in reproduction.

## Key findings

- 1125 proteins were identified in giant panda seminal plasma, related to metabolism and protein turnover.
- Unique proteins, including WD40 repeat-containing proteins, were found to be associated with sperm function and fertility.
- Comparisons with humans, pigs, and sheep revealed distinct protein profiles in giant panda seminal plasma.

## Abstract

For the ex-situ conservation of giant pandas, both collecting and preserving semen are important methods. The seminal plasma is rich in nutrients and bioactive substances, such as proteins, carbohydrates, lipids, amino acids, and hormones, which play an important role in the reproduction and reproductive health of the species. Understanding the composition and function of proteins in the giant panda seminal plasma proteome can provide valuable insights into their reproductive biology and help develop strategies to improve their reproductive success in captivity, which is essential for giant panda conservation. This is the first study to analyze the seminal plasma proteins of giant pandas through proteomics, identifying 1125 proteins. These proteins are related to protein turnover, translation, and metabolism. The seminal plasma proteins of giant pandas were then compared to those of humans, pigs, and sheep, and many unique proteins were found in giant panda samples. Among these proteins, the WD40 repeat-containing proteins have been identified and implicated in sperm function and fertility.