# Apneic Tracheal Stenting Using Femorofemoral Venoarterial Extracorporeal Membrane Oxygenation in a Coronavirus Disease 2019 (COVID-19) Patient With Critical Airway Obstruction: A Case Report

**Authors:** Akira Iwamizu, Shohei Kaneko, Ryosuke Shintani, Haruka Yokoyama, Taiga Ichinomiya, Tetsuya Hara

PMC · DOI: 10.7759/cureus.99671 · 2025-12-19

## TL;DR

A patient with severe airway blockage due to COVID-19 successfully had a tracheal stent placed using a special heart-lung support method to avoid risks to both the patient and healthcare workers.

## Contribution

This case introduces a novel use of femorofemoral VA-ECMO to safely perform apneic tracheal stenting in a high-risk patient with airway obstruction.

## Key findings

- Femorofemoral VA-ECMO enabled safe apneic tracheal stenting in a patient with SVC compression and poor lung function.
- A combination of high-flow ECMO and physiological strategies effectively managed differential hypoxia risks.
- The approach ensured both patient safety and infection control during a high-risk procedure.

## Abstract

Palliative tracheal stenting for severe central airway obstruction in patients with coronavirus disease 2019 (COVID-19) presents a dual challenge: the imminent risk of acute asphyxia during anesthetic induction and the risk of viral transmission to healthcare professionals via aerosols. While extracorporeal membrane oxygenation (ECMO) can serve as a safety bridge to facilitate apneic interventions, conventional venovenous ECMO may not be feasible in patients with superior vena cava (SVC) compression. Femorofemoral venoarterial ECMO (VA-ECMO) is an alternative; however, it carries a substantial risk of differential hypoxia, particularly in patients with poor native lung function. We report a case of a 41-year-old woman with COVID-19 pneumonia and critical tracheal stenosis (luminal diameter 2 mm) caused by mediastinal lymphadenopathy. Given the prohibitive risk of airway collapse and the need for aerosol containment, she underwent successful apneic tracheal stent placement under femorofemoral VA-ECMO support. This approach was employed because SVC compression precluded upper body cannulation, and differential hypoxia was managed using a multifaceted physiological strategy without circuit modification.

A combination of high-flow ECMO, deep anesthesia, pharmacologic cardiac output suppression, and anemia correction effectively mitigated the risk of differential hypoxia. This case demonstrates that femorofemoral VA-ECMO is a safe and effective option for facilitating apneic high-risk airway procedures, simultaneously ensuring airway security and infection control when conventional strategies are insufficient. Further case accumulation is needed to determine the validity and generalizability of these findings.

## Linked entities

- **Diseases:** coronavirus disease 2019 (MONDO:0100096), tracheal stenosis (MONDO:0002568), pneumonia (MONDO:0005249)

## Full-text entities

- **Diseases:** airway collapse (MESH:D001261), hypoxia (MESH:D000860), Airway Obstruction (MESH:D000402), COVID-19 (MESH:D000086382), anemia (MESH:D000740), infection (MESH:D007239), asphyxia (MESH:D001237), tracheal stenosis (MESH:D014135), mediastinal lymphadenopathy (MESH:D008477)
- **Chemicals:** VA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12813298/full.md

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Source: https://tomesphere.com/paper/PMC12813298