# Clinical analysis of laparoscopic pyeloplsty for ureteropelvic junction obstruction in infants under 3 months old

**Authors:** Zedong Bian, Geng Xiong, Tong Liu, Yong Zhi, Ming Liu

PMC · DOI: 10.3389/fped.2025.1714793 · 2026-01-05

## TL;DR

This study shows that laparoscopic pyeloplasty is a safe and effective treatment for infants under 3 months with ureteropelvic junction obstruction.

## Contribution

The study provides evidence that laparoscopic pyeloplasty can be safely used in very young infants with UPJO.

## Key findings

- Laparoscopic pyeloplasty was completed without conversion to open surgery in all cases.
- Infants under 3 months showed similar outcomes to older infants in terms of operative time, hospital stay, and complications.
- No recurrence or reoperation was needed during a median follow-up of 38.65 months.

## Abstract

To evaluate the safety and efficacy of laparoscopic pyeloplasty (LP) in treating ureteropelvic junction obstruction (UPJO) among infants under 3 months of age.

A retrospective analysis was performed on 45 infants with hydronephrosis caused by UPJO treated with LP between January 2019 and December 2024. Patients were divided into two groups by age: 25 infants aged 0–3 months (Group A) and 20 infants aged 4–12 months (Group B). Operative time, hospital stay, complications, anterior–posterior renal pelvic diameter (APD), and minimum renal cortex thickness (Min.RCT) were compared.

All procedures were completed laparoscopically without conversion to open surgery. No significant differences were observed between groups in operative time, postoperative hospital stay, complication rates, postoperative APD, or postoperative Min.RCT. Both groups showed significant improvement in APD reduction and Min.RCT increase compared with baseline. During follow-up (6–63 months, median 38.65), no recurrence or reoperation was required.

LP is a safe and effective treatment for UPJO in infants ≤3 months with surgical indications.

## Linked entities

- **Diseases:** hydronephrosis (MONDO:0005510)

## Full-text entities

- **Diseases:** hydronephrosis (MESH:D006869), UPJO (MESH:C537373)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12813195/full.md

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Source: https://tomesphere.com/paper/PMC12813195