# Anatomical Investigation of the Gluteus Medius Muscle Innervation and Its Topographical Correspondence With Myofascial Trigger Points

**Authors:** Roberto Procópio Pinheiro, Daniela Andrea Medina Macaya, Ana Maria Itezerote, Samir Omar Saleh, Flávio Hojaij, Mauro Andrade, Alfredo Luiz Jacomo, Flavia Emi Akamatsu Jacomo

PMC · DOI: 10.1155/bmri/7544057 · BioMed Research International · 2026-01-18

## TL;DR

This study investigates the relationship between nerve entry points in the gluteus medius muscle and myofascial trigger points, which are linked to hip and lower limb pain.

## Contribution

The study provides new anatomical evidence linking nerve entry points to clinically described myofascial trigger points in the gluteus medius muscle.

## Key findings

- All areas of the gluteus medius were innervated by the superior gluteal nerve.
- Areas II and IV had significantly more nerve entry points, corresponding to clinically described myofascial trigger points.

## Abstract

Hip pain, a common complaint among adults that often causes functional disability, can be caused by femoroacetabular impingement, labral injuries, stress fractures of the femoral neck, avascular necrosis of the femoral head, osteoarthritis of the femoroacetabular joint, hip fractures, greater trochanteric pain syndrome, pathology of the lumbar spine and sacroiliac joint, and myofascial pain syndrome (MPS). MPS is characterized by the presence of hyperirritable nodules, known as myofascial trigger points (MTPs), within muscles and fascia. MTPs limit the range of motion of the joints. Moreover, they induce a local contraction response triggered by mechanical stimulation. The stimulation of MTPs induces pain and sensory changes that can be localized or referred. The MTPs present in the gluteus medius muscle play a role in inducing patellofemoral pain, pain in the lower limbs, anterior region of the knee and thigh, and lower back; however, the anatomy of MTPs remains to be elucidated. This study is aimed at relating the entry points of the superior gluteal nerve into the gluteus medius muscle with the MTPs described in the literature via anatomical dissection.

Twenty gluteus medius muscles of 10 adult cadavers were divided into four areas: posterosuperior, posteroinferior, anterosuperior, and anteroinferior. The distribution of the nerve branches was classified according to these predetermined areas. Statistical analyses were performed using Poisson distribution and logarithmic link function, followed by Bonferroni multiple comparisons (p < 0.05).

All areas of the gluteus medius were innervated by the branches of the superior gluteal nerve. A significantly greater number of nerve entry points was observed in Areas II and IV (posterosuperior and anteroinferior, respectively)

The areas of penetration of the superior gluteal nerve correspond to the clinically described MTPs.

## Linked entities

- **Diseases:** avascular necrosis of the femoral head (MONDO:0054550), myofascial pain syndrome (MONDO:0006862)

## Full-text entities

- **Diseases:** patellofemoral pain (MESH:D046788), avascular necrosis of the femoral head (MESH:D005271), stress fractures of the femoral neck (MESH:D005265), Hip pain (MESH:D010146), hip fractures (MESH:D006620), femoroacetabular impingement (MESH:D057925), MPS (MESH:D009209), labral injuries (MESH:D000070636), osteoarthritis of the femoroacetabular joint (MESH:D010003)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12812865/full.md

## References

88 references — full list in the complete paper: https://tomesphere.com/paper/PMC12812865/full.md

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Source: https://tomesphere.com/paper/PMC12812865