# The development of metastatic meningioma in a canine patient post-immunotherapy case report

**Authors:** Mercy Paine, Tamara Chamberlin, Jennifer Buczek, Jay McDonnell, Mary White

PMC · DOI: 10.3389/fvets.2025.1646793 · Frontiers in Veterinary Science · 2026-01-05

## TL;DR

A Labradoodle with meningioma lived 28 months after treatment, including immunotherapy, and developed metastasis.

## Contribution

This case report documents a rare instance of metastatic meningioma in a dog following immunotherapy.

## Key findings

- The canine patient survived 28 months post-diagnosis with a meningioma that recurred after surgery and immunotherapy.
- The case highlights the potential role of immunotherapy in extending survival and enabling metastatic disease development.

## Abstract

Metastatic meningioma is a rare occurrence in canine patients, with only four previous cases reported. This case report examines a recurrent meningioma with pulmonary metastasis in a male Labradoodle that survived 28 months post clinical presentation. The meningioma recurred following surgery and treatment with an autologous tumor cell lysate vaccine. This case explores the potential role of immunotherapy, by extending survival time, creating conditions that allow for the rare development of metastatic disease.

## Full-text entities

- **Diseases:** pulmonary metastasis (MESH:D009362), tumor (MESH:D009369), Metastatic meningioma (MESH:D008579)
- **Species:** Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12812729/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12812729/full.md

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Source: https://tomesphere.com/paper/PMC12812729