# An exploration and analysis of the role positioning, duty comparison, and career development path of clinical research nurses in developed and developing countries

**Authors:** Xiaotao Cao, Jiaxing Xu, Mingyang Li, Li Zheng

PMC · DOI: 10.3389/fmed.2025.1708032 · Frontiers in Medicine · 2026-01-05

## TL;DR

This paper compares the roles and career paths of clinical research nurses in developed and developing countries, focusing on China.

## Contribution

The study provides a comparative analysis of clinical research nurses' roles and career development in developed and developing countries.

## Key findings

- Clinical research nurses in developed countries have clearer role definitions and career paths.
- China faces challenges in professional recognition and career advancement for clinical research nurses.
- The paper identifies obstacles to career development in China's clinical research nursing field.

## Abstract

With the standardization of the clinical trial industry, clinical research nurses, as core members of multidisciplinary research teams, their role positioning, duties, and career development paths have become critical factors in improving the quality of clinical trials. This review compares and analyses the current practices of clinical research nurses in developed and developing countries, taking China as an example. It sorts out differences in their role perceptions, duty divisions, career promotion paths, and analyses the obstacles affecting the career development of clinical research nurses in China. It aims to provide a useful reference for the professional construction of clinical research nurses in China and other developing countries, help optimize the cultivation mode and management mechanism of clinical research nurses, and then promote the high-quality development of the clinical trial industry in developing countries.

## Full-text entities

- **Diseases:** drug abuse (MESH:D019966), diabetes (MESH:D003920), Cancer (MESH:D009369), CRCs (MESH:D014947), breast cancer (MESH:D001943), cardiovascular disease (MESH:D002318), SAEs (MESH:D064420), CRC (MESH:D015179)
- **Chemicals:** blood glucose (MESH:D001786), CRN (-)
- **Species:** Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12812649/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12812649/full.md

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Source: https://tomesphere.com/paper/PMC12812649