# Geneticization in the genomic era: a scoping review of ethical, clinical, and sociocultural transformations

**Authors:** Safa Shaheen, Mohammed Ghaly

PMC · DOI: 10.3389/fsoc.2025.1675678 · Frontiers in Sociology · 2026-01-05

## TL;DR

This paper reviews how the concept of geneticization has evolved in recent years, highlighting its ethical, clinical, and sociocultural impacts in the genomic era.

## Contribution

The study provides a scoping review of geneticization's transformation and relevance across disciplines since Lippman's original concept.

## Key findings

- Recent scholarship shows a shift from deterministic to more nuanced understandings of geneticization.
- Ongoing risks of genetic reductionism persist in areas like race, identity, and education.
- Geneticization remains a critical lens for evaluating the ethical implications of genetic technologies.

## Abstract

Geneticization is a concept originally introduced by Abby Lippman to critique the growing dominance of genetic explanations in health, identity, and society. Over the decades, the notion of geneticization has undergone significant development across various academic fields including sociology, bioethics, clinical medicine, and cultural studies, highlighting its broad relevance and impact on multiple areas of research. We conducted a scoping review of 25 peer-reviewed studies from 2011 and 2024, to investigate how the concept has been taken up, redefined, and challenged across multiple disciplines. Guided by two central research questions: (1) What are the prevailing themes surrounding geneticization in recent scholarship? and (2) To what extent do Lippman’s original concerns remain relevant? the review synthesizes insights from these studies, categorizing them across sociological, clinical, and ethical dimensions. Findings reveal a shift from deterministic framings toward more complex understandings, such as enlightened geneticization, biosociality, and biological citizenship, which highlight individuals’ agency in interpreting genetic information. At the same time, the review identifies ongoing risks of genetic reductionism in areas such as race, identity, reproduction, and education. The results underscore that while the term “geneticization” has evolved in both use and meaning, it remains a critical analytical lens for evaluating the ethical, legal, and social implications (ELSI) of genetic technologies. The review concludes by emphasizing the continued relevance of interdisciplinary inquiry and ethical vigilance in the genomic era.

## Full-text entities

- **Genes:** UGT2B17 (UDP glucuronosyltransferase family 2 member B17) [NCBI Gene 7367] {aka BMND12, UDPGT2B17}
- **Diseases:** fetal malformations (MESH:D000013), diabetes (MESH:D003920), Down syndrome (MESH:D004314), chromosomal anomalies (MESH:D002869), cancer (MESH:D009369), PND (MESH:D001523), addiction (MESH:D019966), schizophrenia (MESH:D012559), anxiety (MESH:D001007), cystic fibrosis (MESH:D003550), autism (MESH:D001321), MIM (MESH:D030342), congenital disorders (MESH:D009358), discrimination (MESH:D010468), genetic abortion (MESH:D000026), infertility (MESH:D007246), depression (MESH:D003866), breast cancer (MESH:D001943), STS (MESH:C000719218), aggression (MESH:D010554)
- **Chemicals:** epitestosterone (MESH:D004845), green (MESH:C024537), testosterone (MESH:D013739)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12812624/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12812624/full.md

## References

104 references — full list in the complete paper: https://tomesphere.com/paper/PMC12812624/full.md

---
Source: https://tomesphere.com/paper/PMC12812624