# Case Report: A case of cervical burkitt lymphoma and literature review

## TL;DR

This case report describes a rare instance of cervical Burkitt lymphoma in a 55-year-old woman and outlines the diagnostic process.

## Contribution

The novelty lies in the detailed documentation of a rare primary cervical Burkitt lymphoma case with comprehensive diagnostic confirmation.

## Key findings

- The tumor cells showed infiltrative growth and basophilic cytoplasm.
- MYC translocation and IG rearrangement were confirmed through molecular testing.

## Abstract

Primary cervical Burkitt’s lymphoma (BL) is an extremely rare malignancy. This report describes the case of a 55-year-old woman admitted to the hospital with irregular vaginal bleeding. Histologically, the tumor cells demonstrated infiltrative growth, relatively uniform basophilic cytoplasm. Immunohistochemical analysis revealed positivity for B-cell markers (CD20, CD79α, etc.), with MYC expression in approximately 80% of cells, fluorescence in situ hybridization staining showed positivity for MYC translocation and molecular testing confirmed IG rearrangement. The diagnosis of Burkitt’s lymphoma is based on its distinctive histological morphology in combination with immunohistochemistry and molecular testing.