# A Rare Case of Coexisting Medullary and Papillary Thyroid Carcinomas With Parathyroid Adenoma in Pancreatic Neuroendocrine Tumour (pNET)

**Authors:** Nazia Binte Salam, Fahmida Tithi, Sunil Zachariah

PMC · DOI: 10.7759/cureus.99654 · Cureus · 2025-12-19

## TL;DR

A 79-year-old man had rare coexisting thyroid and parathyroid tumors along with a pancreatic tumor, highlighting the need for multidisciplinary care.

## Contribution

This case report documents the rare coexistence of multiple endocrine tumors and suggests potential syndromic associations.

## Key findings

- The patient had medullary and papillary thyroid carcinomas along with a parathyroid adenoma.
- An incidental pancreatic neuroendocrine tumor was also identified.
- The case emphasizes the importance of multidisciplinary collaboration for complex diagnoses.

## Abstract

We present a rare and complex case involving the simultaneous occurrence of medullary thyroid carcinoma (MTC), papillary thyroid carcinoma (PTC), and a parathyroid adenoma in a 79-year-old male. Additionally, incidental radiological findings suggest a pancreatic neuroendocrine tumour (NET). The coexistence of these diverse endocrine disorders is exceptionally uncommon and raises important questions regarding potential syndromic associations. Such cases highlight the necessity for thorough diagnostic evaluation, individualised treatment planning, and the collaboration of a multidisciplinary team, including endocrinologists, oncologists, surgeons, radiologists, and pathologists, to ensure optimal patient outcomes.

## Linked entities

- **Diseases:** medullary thyroid carcinoma (MONDO:0007958), papillary thyroid carcinoma (MONDO:0005075), parathyroid adenoma (MONDO:0006890)

## Full-text entities

- **Diseases:** NET (MESH:D009369), Pancreatic Neuroendocrine Tumour (MESH:D010190), MTC (MESH:C536914), Parathyroid Adenoma (MESH:D010282), endocrine disorders (MESH:D004700), PTC (MESH:D000077273)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12812429/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12812429/full.md

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Source: https://tomesphere.com/paper/PMC12812429