# Genes, Drugs, and Personalized Medicine—The DNA of a Pharmacogenomics Curriculum

## TL;DR

This paper describes a pharmacogenomics curriculum that significantly improved students' ability to apply genomic data to personalized medicine through interactive learning methods.

## Contribution

A novel pharmacogenomics curriculum using constructivist principles and mastery learning that effectively enhances students' clinical application skills.

## Key findings

- Student quiz scores increased from 42% to 90% after completing the curriculum.
- All students reported improved ability to apply genomic data to patient care.
- Students scored ≥85% on performance tasks, demonstrating strong competency.

## Abstract

Precision medicine tailors treatment based on individual genetic, environmental, and lifestyle differences. A key component is pharmacogenomics, which informs drug response and guides personalized care. We developed a pharmacogenomics curriculum for healthcare students using constructivist principles and mastery learning assessment. Activities included case-based quizzes, real-world simulations, and team projects. Among 87 students completing the elective, average quiz scores rose from 42 to 90%, and students scored ≥ 85% on performance tasks. All reported improved ability to apply genomic data to patient care. Our model aligns with genomic EPAs and prepares students for clinical integration.