# Optimizing Dermal Filler for Chin and Jawline Definition as an Advanced Approach for Natural Results: A Prospective Case Series With Ultrasonographic and 3D Facial Imaging Evaluation

**Authors:** Allan Alcantara, Érika Vassoler Guerrero Puccia, Caio Perrella de Rezende, Jun Ho Kim, Renata Viana

PMC · DOI: 10.7759/cureus.99477 · Cureus · 2025-12-17

## TL;DR

This study shows a safe and effective method using hyaluronic acid fillers to enhance chin and jawline appearance with high patient satisfaction.

## Contribution

A novel anatomically guided hyaluronic acid filler technique for minimal-volume, natural-looking facial contouring is introduced and validated.

## Key findings

- All patients showed consistent enhancement in lower face definition.
- 98% patient satisfaction rate was achieved with no major adverse events.

## Abstract

Non-surgical mandibular contouring has gained attention as a safe and effective approach to improve jawline aesthetics and restore lower facial definition. This study aimed to assess the efficacy, safety, and patient satisfaction associated with an anatomically guided hyaluronic acid (HA) filler technique designed to enhance chin projection and mandibular contour using minimal product volume. Ten healthy patients aged 25-45 years underwent individualized treatments guided by facial proportions and anatomical landmarks. A maximum of 6 mL of high elastic modulus (G′) HA filler was administered per patient. Three-dimensional photographic documentation and ultrasound imaging were used to guide applications and monitor outcomes. The results showed consistent enhancement in lower face definition across all patients, with a 98% satisfaction rate and no major adverse events reported. These findings support the use of this anatomically guided protocol as a reproducible and minimally invasive option for lower facial rejuvenation, offering effective aesthetic improvements while maintaining a favorable safety profile.

## Full-text entities

- **Chemicals:** HA (MESH:D006820)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

14 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12811921/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12811921/full.md

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Source: https://tomesphere.com/paper/PMC12811921