# Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization

**Authors:** Allianna Mitchell, Andrew Gessouroun, Wissam El Atrouni, Ryan Kubat, Omar Almoghrabi, Megan Vorhies, Brigid Flynn

PMC · DOI: 10.1155/crdi/4652171 · 2026-01-16

## TL;DR

A 63-year-old man with Bourbon virus infection developed severe organ failure and required life-support measures before dying.

## Contribution

This is the first reported lethal case of Bourbon virus infection with detailed clinical course and outcomes.

## Key findings

- The patient required multiple inotropes, pressor agents, and renal replacement therapy.
- Venoarterial extracorporeal membrane oxygenation (VA-ECMO) was used due to multisystem organ failure.
- The case highlights the severity and potential lethality of Bourbon virus infection.

## Abstract

We present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation. The patient had acute multisystem organ failure requiring multiple inotropes and pressor agents, renal replacement therapy, and venoarterial extracorporeal membrane oxygenation (VA‐ECMO). This report describes the presentation, clinical outcomes, and background on Bourbon virus infection.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** organ failure (MESH:D009102), Shock (MESH:D012769), Bourbon virus infection (MESH:D014777), diabetic (MESH:D003920)
- **Species:** Bourbon virus (no rank) [taxon 1618189], Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12811625/full.md

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Source: https://tomesphere.com/paper/PMC12811625