# What makes a scent trigger a memory? A cognitive decomposition of odor-evoked retrieval

**Authors:** Juliette Greco-Vuilloud, Perrine Ruby, Jane Plailly, Anne-Lise Saive

PMC · DOI: 10.1016/j.isci.2025.114467 · iScience · 2025-12-17

## TL;DR

This study explores how and why certain scents trigger vivid memories, finding that emotional strength and how we describe odors play key roles.

## Contribution

The study empirically dissociates odor recognition and associative memory, revealing distinct predictors for each using machine learning explanations.

## Key findings

- Odor recognition is driven by emotional strength, especially for unpleasant odors.
- Associative memory shows a U-shaped relationship with odor familiarity.
- Semantic distinctiveness enhances odor-evoked memory.

## Abstract

A single scent can unlock vivid memories. This study investigates the factors that make some odors more evocative than others. We examined odor-evoked episodic memory in 106 participants who experienced odors embedded in distinct visuospatial contexts, and whose memory was tested 24–72 h later. The protocol empirically dissociates odor recognition (“I’ve already smelled this scent”) and associative memory (“It evokes a memory”) processes. Using machine learning with SHapley Additive exPlanations, we identified distinct predictors for each process. Recognition was driven by emotional strength, especially for unpleasant odors, and the richness of verbal descriptions. Associative memory followed a U-shaped relationship with familiarity and was strongly influenced by semantic distinctiveness—how uniquely each odor was described. Together, these findings reveal that odor memorability depends not only on its emotional salience but also on how specifically it is conceptualized and how familiar we are with it.

•Odor-evoked memory unfolds into recognition and associative retrieval•Odor recognition is driven by unpleasant emotional strength•Associative retrieval shows a U-shape relationship with odor familiarity•Semantic richness and uniqueness of descriptions enhance odor-evoked memory

Odor-evoked memory unfolds into recognition and associative retrieval

Odor recognition is driven by unpleasant emotional strength

Associative retrieval shows a U-shape relationship with odor familiarity

Semantic richness and uniqueness of descriptions enhance odor-evoked memory

Neuroscience; Cognitive neuroscience; Machine learning

## Full-text entities

- **Genes:** SHROOM4 (shroom family member 4) [NCBI Gene 57477] {aka MRXSSDS, SHAP, shrm4}
- **Chemicals:** methyl octine carbonate (MESH:C055802), essential oils (MESH:D009822), dihydromyrcenol (MESH:C542861)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12808892/full.md

## References

97 references — full list in the complete paper: https://tomesphere.com/paper/PMC12808892/full.md

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Source: https://tomesphere.com/paper/PMC12808892