# Research progress on transcranial direct current stimulation for improving muscle strength: a narrative review

**Authors:** Yiguang Zhang, Yi Zhang, Yu Song, Huaduo Wu, Xin Gao, Yumo Dong, Ning Jiang

PMC · DOI: 10.3389/fneur.2025.1709933 · Frontiers in Neurology · 2026-01-02

## TL;DR

This paper reviews how transcranial direct current stimulation may help improve muscle strength, but findings are inconsistent and more research is needed.

## Contribution

A comprehensive review of tDCS effects on muscle strength, highlighting inconsistencies and suggesting future research directions.

## Key findings

- tDCS may influence muscle strength, but effects vary across individuals and protocols.
- Evidence suggests tDCS impacts maximum strength, explosive power, and endurance.
- Mechanisms of tDCS on muscle strength remain unclear and require further investigation.

## Abstract

Muscle strength plays a fundamental role in enhancing sports performance, preventing sports injuries, and improving overall quality of life. In recent years, transcranial direct current stimulation (tDCS) has garnered significant attention in the field of motor performance enhancement. As a non-invasive brain stimulation technique, tDCS applies weak, constant direct current through electrode plates placed on the scalp to modulate neural excitability in specific areas of the cerebral cortex. However, the effects of tDCS on improving muscle strength remain inconsistent, and its exact mechanisms are still unclear. Further research is warranted to clarify its efficacy. This review summarizes research on the influence of tDCS interventions on muscle strength, focusing on maximum muscle strength, explosive power, and muscle endurance. It aims to analyze the outcomes of tDCS interventions across various sports tasks, and to discuss potential mechanisms through which tDCS may affect muscle strength. The collected evidence suggests that tDCS has the potential to influence muscle strength; however, considerable variations in its effects on athletes’ specific skills may be related to individual differences and varying stimulation protocols. This review consolidates existing evidence and offers relevant suggestions for future research, providing a theoretical foundation for the application of tDCS to improving muscle strength.

## Full-text entities

- **Diseases:** tingling (MESH:D010292), muscle pain (MESH:D063806), depression (MESH:D003866), illnesses (MESH:D002908), pain (MESH:D010146), muscle (MESH:D019042), skin erythema (MESH:D012871), injuries (MESH:D014947), sports injuries (MESH:D001265), mental illnesses (MESH:D001523), fatigue (MESH:D005221), stroke (MESH:D020521)
- **Chemicals:** Ca2+ (-), flunarizine (MESH:D005444), carbamazepine (MESH:D002220), calcium (MESH:D002118), oxygen (MESH:D010100), dextromethorphan (MESH:D003915), glutamate (MESH:D018698)
- **Species:** Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090]

## Full text

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## Figures

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## References

135 references — full list in the complete paper: https://tomesphere.com/paper/PMC12807968/full.md

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Source: https://tomesphere.com/paper/PMC12807968