# Pemphigus foliaceus transforming to pemphigus vulgaris: a case report

**Authors:** Mandlin Abdulaziz Almousa, Navya Kuchibhotla, Lama Alabdulaaly, Marcus Couey, Vikki Noonan, Herve Sroussi

PMC · DOI: 10.3389/fmed.2025.1707841 · Frontiers in Medicine · 2026-01-02

## TL;DR

This case report describes a rare instance where pemphigus foliaceus transformed into pemphigus vulgaris, highlighting an unusual progression in autoimmune skin disease.

## Contribution

The novelty lies in documenting a biopsy-confirmed transition from pemphigus foliaceus to pemphigus vulgaris, a rare clinical phenomenon.

## Key findings

- A biopsy-proven case of pemphigus foliaceus transitioned to pemphigus vulgaris.
- This transformation is uncommon and adds to the understanding of pemphigus subtype dynamics.

## Abstract

Pemphigus represents a family of acantholytic autoimmune vesiculobullous diseases. It is classified into multiple subtypes, the two most common of which are pemphigus vulgaris and pemphigus foliaceus. The transition between these two subtypes is uncommon. In this report, we discuss a unique case of biopsy-proven pemphigus foliaceus transitioning to pemphigus vulgaris.

## Linked entities

- **Diseases:** pemphigus foliaceus (MONDO:0019324), pemphigus vulgaris (MONDO:0008219)

## Full-text entities

- **Diseases:** Pemphigus (MESH:D010392), autoimmune vesiculobullous diseases (MESH:D012872)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12807948/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12807948/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12807948/full.md

---
Source: https://tomesphere.com/paper/PMC12807948