# Meniscus extrusion on standing weightbearing ultrasound is associated with limb alignment and posterior tibial slope in healthy knees

**Authors:** Yunseo Linda Park, Anja M. Wackerle, Jumpei Inoue, Kohei Kamada, Romed P. Vieider, Volker Musahl, Jonathan D. Hughes

PMC · DOI: 10.1002/jeo2.70631 · Journal of Experimental Orthopaedics · 2026-01-15

## TL;DR

This study finds that meniscus extrusion in healthy knees varies with body position and is linked to limb alignment and tibial slope.

## Contribution

The study establishes baseline values for dynamic meniscus extrusion in healthy knees using ultrasound.

## Key findings

- Meniscus extrusion cross-sectional area was greatest in bipodal stance and decreased in supine.
- Greater varus alignment correlated with less lateral meniscus extrusion change.
- Increased posterior tibial slope correlated with greater medial meniscus extrusion.

## Abstract

The purpose of this study was to report meniscus extrusion in asymptomatic knees using ultrasound sonography (US) and evaluate the association between the extrusion and joint space width, coronal alignment, and posterior tibial slope (PTS).

Patients ≥18 years with meniscus allograft transplantation with a contralateral knee that was asymptomatic, Kellgren‐Lawrence grade ≤1, without a history of pathology were included. Knee pain or acute injury requiring orthopaedic evaluation, prior knee surgery, and inflammatory arthropathies were excluded. Meniscus position was captured via US in supine, bipodal, and unipodal stances. Participants underwent radiographic imaging, and joint space width, alignment, and PTS were measured. Statistical analyses included t‐tests, Mann–Whitney U tests, Pearson correlation, Friedman and repeated ANOVA for further comparisons. Statistical significance was set at p < 0.05.

Twenty‐eight patients (mean age: 39 ± 11 years, 36% females) were included. No significant differences were found between medial and lateral extrusion across stances (all p > 0.05; medial 2.7 mm vs. lateral 2.7 mm in supine). Extrusion CSA of the medial meniscus was greatest in the bipodal (22.4mm2), followed by unipodal (21.3mm2), then supine (16.0mm2) stances (p < 0.01). Extrusion distance of both menisci was greatest in the unipodal (medial 3.2 mm, lateral 3.1 mm), followed by bipodal (medial 3.1 mm, lateral 3.0 mm), then supine stances (medial 2.7 mm, lateral 2.7 mm, p < 0.01). Age, body mass index (BMI), and joint space width (medial 7.4 ± 1.5 mm, lateral 7.3 ± 1.4 mm) were not correlated with extrusion (all p > 0.05). For the lateral meniscus, greater varus alignment correlated with less change in extrusion from supine to unipodal (r = –0.70; p < 0.01) and bipodal (r = 0.52; p = 0.02) stances. For the medial meniscus, PTS had a positive correlation with extrusion from supine to unipodal (r = 0.50; p = 0.02) and bipodal (r = 0.53; p = 0.01) stances.

Meniscus extrusion varied with loading conditions and bony morphology. Varus alignment was associated with less lateral meniscus extrusion, and increased PTS with greater medial meniscus extrusion. These results establish baseline values for dynamic meniscus extrusion in healthy knees, to guide US‐based monitoring after surgery.

Level IV, case series.

## Full-text entities

- **Diseases:** Knee pain (MESH:D046788), inflammatory arthropathies (MESH:D007249), acute injury (MESH:D001930), Meniscus extrusion (MESH:D000070600), Varus (MESH:D060905)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12807492/full.md

## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12807492/full.md

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Source: https://tomesphere.com/paper/PMC12807492