# Electroacupuncture reshapes the microbial co‐occurrence networks related to the behavioral and psychological symptoms of dementia in Alzheimer's disease

## TL;DR

Electroacupuncture can change gut microbes linked to dementia symptoms in Alzheimer's disease, offering new treatment insights.

## Contribution

The study demonstrates electroacupuncture's potential to reshape gut microbial networks in Alzheimer's-related dementia symptoms.

## Key findings

- Microbial keystone species and gut composition vary with Alzheimer's-related dementia symptoms.
- Electroacupuncture alters the intestinal microbial landscape in Alzheimer's disease.
- Age stratification reveals stage-specific gut microbial signatures in BPSD.

## Abstract

Microbial keystone species and gut microbiota composition are highly variable during the pathological development of the behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD). Age stratification reveals stage‐specific gut microbial signatures in AD‐related BPSD. This study highlights the efficacy of electroacupuncture in regard to altering the intestinal microbial landscape in AD‐related BPSD and provides novel insights into the application of phased targeted electroacupuncture interventions in the future.