# A home-based VR exercise for improving depression and quality of life after heart surgery: a randomized controlled trial

**Authors:** Kornanong Yuenyongchaiwat, Natsinee Sermsinsaithong, Chatchai Buekban, Chusak Thanawattano, Wararat Tavonudomgit, Chitima Kulchanarat, Khanistha Wattanananont, Sasipa Buranapuntalug, Preeyaphorn Songsorn, Opas Satdhabudha

PMC · DOI: 10.1080/21642850.2026.2614807 · Health Psychology and Behavioral Medicine · 2026-01-13

## TL;DR

A home-based VR exercise program reduced depression in heart surgery patients but did not improve quality of life.

## Contribution

Demonstrates that VR-based exercise can be a novel strategy for mental health support in post-surgery cardiac rehab.

## Key findings

- VR group showed significant reduction in depression after eight weeks compared to the control group.
- No significant improvement in quality of life (SF-36 scores) was observed between the groups.

## Abstract

Exercise is an integral component of cardiac rehabilitation after open-heart surgery in both hospital and community settings, and such programs are designed to reduce adverse physical and mental health outcomes in patients undergoing cardiac surgery. Virtual reality (VR)-based aerobic exercises are used for cardiac rehabilitation. We aimed to analyze the effects of an eight-week home-based phase II cardiac rehabilitation program performed in VR on depression and quality of life (QOL) in community-dwelling individuals who underwent open-heart surgery.

A randomized controlled trial was conducted, and 49 patients who underwent elective open-heart surgery were assigned to either the VR group (n=24) or the control group. Members of the control group received a paper booklet (n=25) during phase II cardiac rehabilitation. Depression and SF-36 scores were assessed at baseline and at eight weeks.

The VR group showed a significant decrease in depression after eight weeks, compared to the control group (D-1.75, p=.003, n2p=0.175). The SF-36 showed no significant differences between the VR and control groups.

A home-based VR exercise program has applications in phase II cardiac rehabilitation for open-heart surgery by reducing depression but not QOL. Therefore, integrating VR exercise into cardiac rehabilitation programs may offer a novel strategy to address mental health challenges.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** Depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12805847/full.md

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Source: https://tomesphere.com/paper/PMC12805847