# First person – Camille Lacarrière-Keïta

## TL;DR

Camille Lacarrière-Keïta discusses her research on autophagy inhibition in intestinal stem cells and its impact on cell differentiation.

## Contribution

The study reveals how autophagy inhibition promotes enteroendocrine cell differentiation via Stat92E activity in intestinal stem cells.

## Key findings

- Inhibiting autophagy in intestinal stem cells increases enteroendocrine cell differentiation.
- Stat92E activity is crucial for this differentiation process.
- The findings provide insights into intestinal cell development and disease mechanisms.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Camille Lacarrière-Keïta is first author on ‘
Autophagy inhibition in intestinal stem cells favors enteroendocrine cell differentiation through Stat92E activity’, published in DMM. Camille conducted the research described in this article while a PhD student in Professor Steve Jean's lab at Université de Sherbrooke, Sherbrooke, Canada. She is now a postdoc researcher in the lab of Dr Edward A. Fon and Dr Ziv Gan-Or at McGill University, Ville-Marie, Canada, investigating GCase lysosomal trafficking and activity in dopaminergic neurons harbouring a reduced expression of lysosomal Parkinson's disease-risk genes.