# Novel isochromosome 7q and NOTCH1 mutation in an 88-year-old male with Sézary syndrome

**Authors:** Nicole Loranger, Nicole Trepanowski, Jeremiah X. Karrs, Wahab A. Khan, Parth Shah, Joi B. Carter, Frederick Lansigan

PMC · DOI: 10.1016/j.jdcr.2025.09.030 · 2025-10-10

## Full-text entities

- **Genes:** NOTCH1 (notch receptor 1) [NCBI Gene 4851] {aka AOS5, AOVD1, TAN1, hN1}
- **Diseases:** Sezary syndrome (MESH:D012751)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12805244/full.md

---
Source: https://tomesphere.com/paper/PMC12805244