# Radiologic Features of Curvilinear and Tubulonodular Pericallosal Lipomas: Two Case Reports

**Authors:** Abdelwahed Diani, Fatima-Ezzahra Akhatar, Mohammed reda Bouroumane, Meriam Benzalim, Soumaya Alj

PMC · DOI: 10.7759/cureus.99319 · 2025-12-15

## TL;DR

This paper presents two case reports of rare brain lipomas, highlighting how imaging helps distinguish between curvilinear and tubulonodular types.

## Contribution

The paper contributes two distinct clinical cases that illustrate the diagnostic value of imaging for pericallosal lipoma subtypes.

## Key findings

- A curvilinear pericallosal lipoma was identified in a 35-year-old woman with helmet-like headaches via MRI.
- A tubulonodular pericallosal lipoma was found in a 33-year-old man following a minor trauma using CT and MRI.
- Imaging is crucial for distinguishing between the two morphological subtypes of pericallosal lipomas.

## Abstract

Pericallosal lipomas or lipomas of the corpus callosum are rare, benign, fat-containing congenital brain lesions. They may occur in isolation or be associated with corpus callosum dysgenesis or agenesis. Therefore, they have a broad clinical presentation, ranging from being totally asymptomatic to having seizures, motor deficits, or headaches. Imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) are key to diagnosis, allowing recognition of two morphological subtypes: tubulonodular and curvilinear.

In this article, we report two cases. The first concerns a 35-year-old woman evaluated for helmet-like headaches, in whom a brain MRI demonstrated a curvilinear lipoma of the corpus callosum. The second case concerns a 33-year-old man with headaches following a benign trauma, in whom CT and MRI identified a tubulonodular corpus callosum lipoma. These cases emphasize the significance of imaging in distinguishing between these two forms.

## Full-text entities

- **Diseases:** trauma (MESH:D014947), motor deficits (MESH:D009461), headaches (MESH:D006261), congenital brain lesions (MESH:D001927), corpus callosum dysgenesis (MESH:D061085), agenesis (MESH:C536482), Pericallosal Lipomas (MESH:D008067), seizures (MESH:D012640)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12803705/full.md

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Source: https://tomesphere.com/paper/PMC12803705