# Use of Stent Retriever Thrombectomy Combined With Local Urokinase Thrombolysis for Deep Cerebral Vein Thrombosis: A Case Report

**Authors:** Qunli Xu, Yigang Chen, Xu Zheng, Xing Jin, Jinhua Zhang

PMC · DOI: 10.3389/fstro.2022.901694 · Frontiers in Stroke · 2022-07-14

## TL;DR

This case report describes a successful treatment for a rare brain vein clot using a stent and local clot-dissolving drug.

## Contribution

First reported use of stent retriever thrombectomy with local urokinase for deep cerebral vein thrombosis.

## Key findings

- Stent retriever thrombectomy combined with local urokinase thrombolysis was technically feasible.
- Recanalizing the vein of Galen was key to restoring deep cerebral vein outflow.
- The treatment led to successful recovery in a patient with deep cerebral vein thrombosis.

## Abstract

Deep cerebral vein (DCV) thrombosis is a rare type of cerebrovascular disorder and usually has an unfavorable prognosis. Although endovascular treatment measures for venous sinus thrombosis are well-described and evidenced, relevant reports on DCV thrombosis are presently lacking.

In this report, we present the first case of the successful use of stent retriever thrombectomy combined with local urokinase thrombolysis for DCV thrombosis and have described the detailed procedure.

The use of stent retriever thrombectomy combined with local thrombolysis was technically feasible and effective for DCV thrombosis. The key to the successful restoration of DCV outflow was to recanalize the occluded vein of Galen.

## Full-text entities

- **Diseases:** Cerebral Vein Thrombosis (MESH:D020767), DCV thrombosis (MESH:D020246), cerebrovascular disorder (MESH:D002561), venous sinus thrombosis (MESH:D012851)

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12802700/full.md

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Source: https://tomesphere.com/paper/PMC12802700