# Negative Pressure Wound Therapy in an Immunocompromised Child: A Case Report From a Resource‐Limited Setting in Ghana

**Authors:** Matilda Mawusi Kodjo, Kennedy Kofi Kru, Belinda Dziedzorm Korley, Cynthia Tetteh, Wise Awunyo, Agani Afaya

PMC · DOI: 10.1002/ccr3.71846 · Clinical Case Reports · 2026-01-14

## TL;DR

A child with a large wound in Ghana healed quickly using a makeshift negative pressure wound therapy device, showing it can work even in resource-limited settings.

## Contribution

Demonstrates the effectiveness of improvised negative pressure wound therapy in a resource-limited setting for rapid healing in an immunocompromised child.

## Key findings

- The wound showed massive improvement within the first week of using the improvised device.
- Healthy granulation tissue filled the wound by the third day of treatment.
- The therapy worked effectively despite the patient's immunocompromised status.

## Abstract

An 8‐year‐old immunocompromised girl with a large septic wound on the left thigh was admitted to the facility after the failure of home treatment by the family. The child was generally stable aside from the difficulty in walking on the left leg. An improvised vacuum‐assisted closure device was used to promote wound healing, as the actual device was not available. The wound experienced massive and impressive improvement within the first week of admission. Healthy and beautiful granulation tissues filled up the depth of the wound, closing it up by the third day of wound dressing. This case illustrates the possibility of healing large wounds faster than expected using negative pressure wound therapy, where the patient's immune status does not affect the healing process. This can be employed to reduce patients' length of hospital stay as well as reduce the workload on staff.

Negative pressure wound therapy enhances rapid wound healing, regardless of wound size and immune status, in children. This method has proven to be effective even with improvised items.

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** septic (MESH:D001170)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12800922/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12800922/full.md

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Source: https://tomesphere.com/paper/PMC12800922