# Lung transplantation for chronic thromboembolic pulmonary hypertension

**Authors:** Laurent Godinas, Michaela Orlitová, Emanuele Muscogiuri, Laurens Ceulemans, Elie Fadel, Marion Delcroix, Tom Verbelen

PMC · DOI: 10.1016/j.jhlto.2025.100461 · JHLT Open · 2025-12-03

## TL;DR

This paper reviews the changing role of lung transplantation for chronic thromboembolic pulmonary hypertension due to recent treatment advances.

## Contribution

The paper provides an updated overview of the current status and specific considerations of lung transplantation for CTEPH.

## Key findings

- Recent therapeutic advances have significantly improved CTEPH patient outcomes.
- Lung transplantation is now less commonly required for CTEPH due to better treatment options.
- The paper highlights the remaining role and unique aspects of lung transplantation for CTEPH.

## Abstract

Therapeutic advances in chronic thromboembolic pulmonary hypertension (CTEPH) over the last 10 years have improved patient prognosis. As a result, the role of lung transplantation (LTx) for this indication has been greatly reduced. In this review article, we describe the evolution of treatments for CTEPH, the place that remains for lung transplantation, and the particularities of lung transplantation for this indication.

## Linked entities

- **Diseases:** chronic thromboembolic pulmonary hypertension (MONDO:0013024)

## Full-text entities

- **Diseases:** CTEPH (MESH:D011655)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12800618/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12800618/full.md

## References

70 references — full list in the complete paper: https://tomesphere.com/paper/PMC12800618/full.md

---
Source: https://tomesphere.com/paper/PMC12800618